NCT05492266 Expiratory Muscle Strength Training for Hypernasal Speech in Children
| NCT ID | NCT05492266 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Noel Jabbour |
| Condition | Velopharyngeal Insufficiency |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-03-03 |
| Primary Completion | 2027-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-03-03 with a primary completion date of 2027-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insufficiency. The purpose of this research study is to test if soft palate exercises using a hand help breathing device will help improve the ability of the soft palate to close the area between the throat and nose and help improve speech.
Eligibility Criteria
Inclusion Criteria: * Score of 2 or greater on the nasality/resonance domain of the Pittsburgh Weighted Speech Scale * Ages 5-17 years Exclusion Criteria: * CAPS-A-AM hypernasality score \<2 * Previous speech surgery (e.g. palatoplasty or pharyngeal flap for speech) * Speech surgery scheduled within the next 56 days * Unable or unwilling to perform the tests and exercises outlined in the study
Contact & Investigator
Noel Jabbour, MD
PRINCIPAL INVESTIGATOR
University of Pittsburgh
Frequently Asked Questions
Who can join the NCT05492266 clinical trial?
This trial is open to participants of all sexes, aged 5 Years or older, up to 17 Years, studying Velopharyngeal Insufficiency. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05492266 currently recruiting?
Yes, NCT05492266 is actively recruiting participants. Contact the research team at shafferad@upmc.edu for enrollment information.
Where is the NCT05492266 trial being conducted?
This trial is being conducted at Pittsburgh, United States.
Who is sponsoring the NCT05492266 clinical trial?
NCT05492266 is sponsored by Noel Jabbour. The principal investigator is Noel Jabbour, MD at University of Pittsburgh. The trial plans to enroll 30 participants.