NCT05775484 Exercise to Slow Cardiovascular Ageing Progression
| NCT ID | NCT05775484 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Heart Centre Singapore |
| Condition | Cardiac Ageing |
| Study Type | OBSERVATIONAL |
| Enrollment | 450 participants |
| Start Date | 2023-05-01 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 450 participants in total. It began in 2023-05-01 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In ageing, deleterious alterations in cardiovascular (CV) structure and function increase risks of ageing-related cardiovascular disease (CVD). Investigators found that these CV alterations were associated with circulating serum metabolites, suggesting a metabolic basis to CV ageing. Investigators hypothesize that modification of these metabolites by intervention, such as exercise, may retard CV alterations and reduce CVD in ageing.
Eligibility Criteria
Inclusion Criteria: * Age \>=21 years old * Outdoor ambulant Exclusion Criteria: * Wheelchair or bed-bound * Dementia * Residing in sheltered or nursing home * Cancer * Participation in ongoing clinical trials that involve interventional drugs or devices * Aneurysms * Acute infections (in the last six months) * Uncontrolled thyrotoxicosis * Neuromuscular, musculoskeletal or rheumatoid disorders that are exacerbated by exercise * Uncontrolled asthma or chronic lung disease * Restrictive lung disease
Frequently Asked Questions
Who can join the NCT05775484 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 100 Years, studying Cardiac Ageing. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05775484 currently recruiting?
Yes, NCT05775484 is actively recruiting participants. Visit ClinicalTrials.gov or contact National Heart Centre Singapore to inquire about joining.
Where is the NCT05775484 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT05775484 clinical trial?
NCT05775484 is sponsored by National Heart Centre Singapore. The trial plans to enroll 450 participants.