NCT06735378 Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury
| NCT ID | NCT06735378 |
| Status | Recruiting |
| Phase | — |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's |
| Condition | Hemodialysis |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-01-20 |
| Primary Completion | 2025-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-01-20 with a primary completion date of 2025-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this study is to determine what happens to the heart muscle contraction when people cycle before their hemodialysis treatment. Will pre-dialysis exercise protect the heart from a decrease in pumping of the heart muscle (called stunning) that can happen during hemodialysis. We will study whether pre-dialysis exercise decreases heart stunning, decreases the number and severity of symptoms commonly associated with hemodialysis, and other outcomes
Eligibility Criteria
Inclusion Criteria: * must be on chronic hemodialysis for at least 3 months * age 18 years or older * willing and able to provide informed consent * assessed to be safe and able to exercise by unit HD Nephrologist Exclusion Criteria: * regular vigorous exercise outside of hemodialysis * over 79 years of age * intradialytic exercise \< 3 months * poor echogenicity * acute coronary syndrome in the past 3 months * unstable arrhythmia/angina * shortness of breath at rest or with minimal activity * symptomatic hypoglycemia (\>2x/week in the week prior to enrolment)
Contact & Investigator
Christopher McIntyre
PRINCIPAL INVESTIGATOR
London Health Sciences Centre Research Institute
Frequently Asked Questions
Who can join the NCT06735378 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 79 Years, studying Hemodialysis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06735378 currently recruiting?
Yes, NCT06735378 is actively recruiting participants. Contact the research team at jarrin.penny@lhsc.on.ca for enrollment information.
Where is the NCT06735378 trial being conducted?
This trial is being conducted at London, Canada.
Who is sponsoring the NCT06735378 clinical trial?
NCT06735378 is sponsored by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's. The principal investigator is Christopher McIntyre at London Health Sciences Centre Research Institute. The trial plans to enroll 30 participants.