NCT07232511 Exercise-induced Hypoalgesia Effects of Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain
| NCT ID | NCT07232511 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Valencia |
| Condition | Rotator Cuff Related Shoulder Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-03-05 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-03-05 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to compare the effects of blood flow restricted (BFR) exercise and to examine the differences between various BFR protocols on acute pain reduction in individuals with rotator cuff-related shoulder pain, as well as the exercise tolerance at each intensity and occlusion setting. There are four exercise modalities corresponding to different combinations of intensity (%RM) and percentage of occlusion (%AOP): 1) 30% RM and 30% AOP; 2) 30% RM and 50% AOP; 3) 30% RM and 70% AOP; 4) 30% RM and BFR placebo (cuff without pressure). All participants will complete one session of each of the four exercise modalities, analyzing the variables studied in each for subsequent analysis and comparison.
Eligibility Criteria
Inclusion Criteria: * Age between 18 and 65 * Shoulder symptoms lasting at least 3 months * Pain in the proximal anterolateral aspect of the shoulder, aggravated by abduction * At least two of the following tests positive: Jobe test, resisted external rotation test, Hawkins-Kennedy test, Neer test, painful arc between 60 and 120 degrees of shoulder abduction Exclusion Criteria: * History of shoulder trauma or surgery * Pain of such intensity that it is impossible to perform the proposed exercises * Active arm elevation less than 90 degrees * Clinical signs of a complete tear (positive delayed external and internal rotation sign and positive arm drop test) * Suspected frozen shoulder (50% reduction or more than 30° loss in passive shoulder external rotation) * Primary diagnosis of shoulder instability or acromioclavicular pathology * Shoulder pain due to primary involvement in the cervical or thoracic region * Corticosteroid injections in the last 6 weeks * Presence of diseases such as inflammatory arthritis, neurological diseases, fibromyalgia, malignant tumors, or polymyalgia rheumatica * Presence of more than one risk factor for thromboembolism * Participation in upper limb exercise programs in the last month
Contact & Investigator
Adrian Escriche-Escuder, PhD
PRINCIPAL INVESTIGATOR
University of Valencia
Frequently Asked Questions
Who can join the NCT07232511 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Rotator Cuff Related Shoulder Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07232511 currently recruiting?
Yes, NCT07232511 is actively recruiting participants. Contact the research team at adrian.escriche@uv.es for enrollment information.
Where is the NCT07232511 trial being conducted?
This trial is being conducted at Valencia, Spain.
Who is sponsoring the NCT07232511 clinical trial?
NCT07232511 is sponsored by University of Valencia. The principal investigator is Adrian Escriche-Escuder, PhD at University of Valencia. The trial plans to enroll 30 participants.