NCT06212791 EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
| NCT ID | NCT06212791 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Virginia Commonwealth University |
| Condition | Paroxysmal Atrial Fibrillation |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-12-26 |
| Primary Completion | 2028-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2024-12-26 with a primary completion date of 2028-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years * Diagnosis of paroxysmal AF * Left ventricular ejection fraction ≥50% * Scheduled for catheter ablation * Able to speak, hear, and read English * Willing and able to provide informed consent Exclusion Criteria: * Persistent or permanent AF * Prior ablation (catheter based or surgical) for AF * Significant sinus node dysfunction * Implanted pacemaker or defibrillator * Contraindication to or inability to complete cardiovascular magnetic resonance study * Contraindication to or inability to complete exercise testing * Chronic kidney disease with estimated glomerular filtration rate \<30 mL/min/1.73m2 * Severe left ventricular hypertrophy * Unrelated cardiomyopathy that is expected to limit exercise capacity, including but not limited to: * Hypertrophic cardiomyopathy * Cardiac amyloidosis * Constrictive pericarditis * Pulmonary arterial hypertension * Prior cardiac surgery * Active pregnancy
Contact & Investigator
Cory Trankle
PRINCIPAL INVESTIGATOR
Virginia Commonwealth University
Frequently Asked Questions
Who can join the NCT06212791 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Paroxysmal Atrial Fibrillation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06212791 currently recruiting?
Yes, NCT06212791 is actively recruiting participants. Contact the research team at pamela.grizzard@vcuhealth.org for enrollment information.
Where is the NCT06212791 trial being conducted?
This trial is being conducted at Richmond, United States.
Who is sponsoring the NCT06212791 clinical trial?
NCT06212791 is sponsored by Virginia Commonwealth University. The principal investigator is Cory Trankle at Virginia Commonwealth University. The trial plans to enroll 50 participants.
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