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Recruiting NCT04822649

NCT04822649 Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition

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Clinical Trial Summary
NCT ID NCT04822649
Status Recruiting
Phase
Sponsor Korea University Anam Hospital
Condition Heart Failure With Preserved Ejection Fraction (HFpEF)
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2021-04-15
Primary Completion 2025-12-31

Eligibility & Interventions

Sex All sexes
Min Age 20 Years
Max Age 80 Years
Study Type INTERVENTIONAL
Interventions
Adenosine stress echocardiography with the evaluation of coronary artery blood flow

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 100 participants in total. It began in 2021-04-15 with a primary completion date of 2025-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The correlation of coronary microvascular function and body composition with cardiopulmonary exercise capacity will be assessed in patients with heart failure with preserved ejection fraction.

Eligibility Criteria

Inclusion Criteria: * Age 20 to 80 * Typical/atypical chest pain or ischemic symptoms including dyspnea * No significant coronary artery stenosis (\>50% stenosis) in coronary angiography or computed tomography * Left ventricular ejection fraction ≥50% Exclusion Criteria: * More than moderate valvular heart disease * Congenital heart disease * Chronic renal failure (estimated glomerular filtration rate \<30 ml/min/1.73m2) or end-stage renal failure undergoing hemodialysis or peritoneal dialysis * Asthma, chronic obstructive pulmonary disease and primary pulmonary hypertension * Receiving anticancer drugs * Vasculitis associated with autoimmune diseases * Patients with difficulty in performing exercise load evaluation (treadmill, bicycle ergometer) * Atrial fibrillation * Atrioventricular block with more than second degrees, symptomatic bradycardia, cryo-node failure syndrome, Wolff-Parkinson-White (WPW) patients

Contact & Investigator

Central Contact

So Ree Kim, MD

✉ soree8826kim@gmail.com

📞 821094534810

Frequently Asked Questions

Who can join the NCT04822649 clinical trial?

This trial is open to participants of all sexes, aged 20 Years or older, up to 80 Years, studying Heart Failure With Preserved Ejection Fraction (HFpEF). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04822649 currently recruiting?

Yes, NCT04822649 is actively recruiting participants. Contact the research team at soree8826kim@gmail.com for enrollment information.

Where is the NCT04822649 trial being conducted?

This trial is being conducted at Seoul, South Korea.

Who is sponsoring the NCT04822649 clinical trial?

NCT04822649 is sponsored by Korea University Anam Hospital. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology