NCT04916327 Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1
| NCT ID | NCT04916327 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Virginia Commonwealth University |
| Condition | Peripheral Vascular Diseases |
| Study Type | INTERVENTIONAL |
| Enrollment | 720 participants |
| Start Date | 2021-08-23 |
| Primary Completion | 2026-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 720 participants in total. It began in 2021-08-23 with a primary completion date of 2026-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).
Eligibility Criteria
Inclusion Criteria: * apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease * for PTSD group, a score of ≥ 33 on PCL-5 checklist * for GAD group, a score of ≥ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist * for Healthy Control group, a score of ≤ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist Exclusion Criteria: * taking medications that could influence cardiovascular function * current smokers who have recently quit smoking * illicit drug use or excessive alcohol consumption * pregnant women * significant calorie restriction or vitamin/mineral deficiencies * limited English proficiency
Contact & Investigator
Ryan Garten, PhD
PRINCIPAL INVESTIGATOR
Virginia Commonwealth University
Frequently Asked Questions
Who can join the NCT04916327 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 35 Years, studying Peripheral Vascular Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04916327 currently recruiting?
Yes, NCT04916327 is actively recruiting participants. Contact the research team at rsgarten@vcu.edu for enrollment information.
Where is the NCT04916327 trial being conducted?
This trial is being conducted at Richmond, United States.
Who is sponsoring the NCT04916327 clinical trial?
NCT04916327 is sponsored by Virginia Commonwealth University. The principal investigator is Ryan Garten, PhD at Virginia Commonwealth University. The trial plans to enroll 720 participants.