Examination of Transcranial Focused Ultrasound on Brain Activity in Adults
Trial Parameters
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Brief Summary
The investigators aim to examine the immediate effect of transcranial focused ultrasound (tFUS) on brain activity in healthy adults.
Eligibility Criteria
Inclusion Criteria: * No present/lifetime history of major depressive disorder (MDD), psychosis, Bipolar Disorder; Hamilton Depression Rating Scale (HDRS)\>7; Young Mania Rating Scale (YMRS)\>10), borderline personality disorder, and present suicidal ideation * No family history of MDD, psychosis, Bipolar Disorder, or epilepsy Exclusion Criteria: * Present/lifetime history of MDD, psychosis, Bipolar Disorder (HDRS\>7; YMRS\>10), borderline personality disorder, and present suicidal ideation. Childhood history of, but not present, anxiety disorders and Attention-deficit/hyperactivity disorder (ADHD) will be allowed as these are common disorders in childhood * Family history of MDD, psychosis, Bipolar Disorder, or epilepsy * History of head injury, neurological (e.g., epilepsy), pervasive developmental disorder (e.g., autism), systemic medical disease and treatment (medical records, participant report) * Use of substances with seizure risk (e.g., stimulants) in the past month, as for oth