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Recruiting NCT05692726

NCT05692726 Evaluation of Volume and Electrolyte Balance in Hyponatremia Treatment - a Prospective Observational Trial

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Clinical Trial Summary
NCT ID NCT05692726
Status Recruiting
Phase
Sponsor University of Cologne
Condition Non-hypervolemic Hyponatremia
Study Type OBSERVATIONAL
Enrollment 50 participants
Start Date 2022-10-15
Primary Completion 2026-09-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Patients

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 50 participants in total. It began in 2022-10-15 with a primary completion date of 2026-09-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

To assess quantitatively the evolution over time of electrolyte-free water clearance and electrolyte mass balance in patients with non-hypervolemic hypotonic hyponatremia

Eligibility Criteria

Inclusion Criteria: * Adult patients ≥ 18 years * Hypotonic hyponatremia * glucose-corrected plasma sodium \<130 mmol/l * serum osmolality \<280 mosmol/kg or lack of signs of non-hypotonic hyponatremia Exclusion Criteria: * Signs of extracellular volume expansion * Patients with liver cirrhosis and severe liver damage AST/ALT\>3xULN, AP\>6xULN, Bilirubin ≥ 3mg/dl * Patients with heart failure * Patients on dialysis and/or patients with oliguric renal impairment and plasma creatinine ≥ 3mg/dl * Patients after organ transplantation

Contact & Investigator

Central Contact

Volker Burst, MD, Prof

✉ volker.burst@uk-koeln.de

📞 +49 221-478-97222

Principal Investigator

Volker Burst, MD, Prof.

PRINCIPAL INVESTIGATOR

University Hospital of Cologne

Frequently Asked Questions

Who can join the NCT05692726 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Non-hypervolemic Hyponatremia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05692726 currently recruiting?

Yes, NCT05692726 is actively recruiting participants. Contact the research team at volker.burst@uk-koeln.de for enrollment information.

Where is the NCT05692726 trial being conducted?

This trial is being conducted at Cologne, Germany.

Who is sponsoring the NCT05692726 clinical trial?

NCT05692726 is sponsored by University of Cologne. The principal investigator is Volker Burst, MD, Prof. at University Hospital of Cologne. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology