NCT07892703 Evaluation of Three Different Intra-canal Medicaments
| NCT ID | NCT07892703 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Minia University |
| Condition | Periapical Healing |
| Study Type | INTERVENTIONAL |
| Enrollment | 45 participants |
| Start Date | 2025-12-16 |
| Primary Completion | 2026-12-10 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 45 participants in total. It began in 2025-12-16 with a primary completion date of 2026-12-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Periapical lesions are the commonly occurring pathologic lesions that affect the periradicular tissues of the tooth . This lesion can be classified as granuloma, cystic, or abscess .The pathologic changes seen in some periradicular and periapical cases are due to the presence of microorganisms, and their byproducts. These released toxins have the ability to diffuse through inflamed pulpal tissue and get into the periapical area. In a necrotic pulp, the lack of blood flow in the root prevents host immunity from eliminating the infection
Eligibility Criteria
Inclusion Criteria: * Patients with mature teeth. * Patients with periapical periodontitis. * Maxillary anterior teeth only will be involved. * Patients should be free from any systemic disease that may affect normal healing and predictable outcome. * Patients who will agree to the consent and will commit to follow-up period. Exclusion Criteria: * Patients with immature roots. * Patients with any systemic disease that may affect normal healing. * Patients with swelling. * Pregnant females. * Patients who could/would not participate in a 1-year follow-up. 6-Patients with old age. * Teeth with periodontal involvement. 8-Teeth with vertical root fractures. * Non-restorable teeth. * cases with previously initiated endodontic treatment.
Contact & Investigator
Dalia Ali Ahmed Moukarab, M.D
STUDY CHAIR
Professor and head of department of Endodontics, Faculty of Dentistry, Minia University
Frequently Asked Questions
Who can join the NCT07892703 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, up to 45 Years, studying Periapical Healing. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07892703 currently recruiting?
Yes, NCT07892703 is actively recruiting participants. Contact the research team at drshimamarof@gmail.com for enrollment information.
Where is the NCT07892703 trial being conducted?
This trial is being conducted at Minya, Egypt.
Who is sponsoring the NCT07892703 clinical trial?
NCT07892703 is sponsored by Minia University. The principal investigator is Dalia Ali Ahmed Moukarab, M.D at Professor and head of department of Endodontics, Faculty of Dentistry, Minia University. The trial plans to enroll 45 participants.