NCT06483646 Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis Diagnosis
| NCT ID | NCT06483646 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Strasbourg, France |
| Condition | Halitosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2024-10-01 |
| Primary Completion | 2025-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2024-10-01 with a primary completion date of 2025-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Halitosis or bad breath is a problem affecting 30% of the world's population. There are many causes, and oral pathologies, including periodontitis, are the main etiology. In order to make a diagnosis, a clinical interview is necessary to distinguish true halitosis from psychological halitosis. In addition, a measurement of volatile sulfur compounds (VSC), the main molecules involved in bad breath, is necessary. This is done during the consultation by measuring the concentration of VSCs in exhaled air. However, few private practices or hospitals have the necessary equipment to measure VSC. As a result, patients are often obliged to travel long distances to obtain a consultation including this specific VSC analysis. The aim of this study is to evaluate the stability of VSC values obtained in gaseous samples up to 7 days after sampling, in order to assess the clinical relevance of analyzing samples at a distance from sampling. The clinical aim is to determine whether self-sampling by the patient at home and extemporaneous analysis could be considered in the diagnosis of halitosis.
Eligibility Criteria
Inclusion Criteria: * Adult, male or female * Subject affiliated with a social health insurance plan * Able to understand the objectives and risks of the research and to give dated and signed informed consent * Subject presenting for consultation for diagnosis and treatment of periodontal pathology Exclusion Criteria: * Subject under safeguard of justice * Subject under guardianship or curatorship * Pregnancy or breast-feeding * Impossibility of giving the subject informed information (subject in emergency situation, difficulties in understanding the subject, etc.) * Subject currently included in another clinical research protocol or in an exclusion period
Frequently Asked Questions
Who can join the NCT06483646 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Halitosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06483646 currently recruiting?
Yes, NCT06483646 is actively recruiting participants. Visit ClinicalTrials.gov or contact University Hospital, Strasbourg, France to inquire about joining.
Where is the NCT06483646 trial being conducted?
This trial is being conducted at Strasbourg, France.
Who is sponsoring the NCT06483646 clinical trial?
NCT06483646 is sponsored by University Hospital, Strasbourg, France. The trial plans to enroll 100 participants.