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Recruiting NCT05241405

NCT05241405 Evaluation of the Impact of Taking American Ginseng for 8 Weeks on Fatigue in Patients Treated for Localized Breast or Gynecological Cancer

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Clinical Trial Summary
NCT ID NCT05241405
Status Recruiting
Phase
Sponsor Centre Francois Baclesse
Condition Breast Cancer
Study Type INTERVENTIONAL
Enrollment 354 participants
Start Date 2022-09-27
Primary Completion 2027-09

Trial Parameters

Condition Breast Cancer
Sponsor Centre Francois Baclesse
Study Type INTERVENTIONAL
Phase N/A
Enrollment 354
Sex FEMALE
Min Age 18 Years
Max Age N/A
Start Date 2022-09-27
Completion 2027-09
Interventions
QISENGPLACEBO

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Brief Summary

This is a multicenter randomized trial in breast cancer patients reporting cancer-related fatigue to evaluate the efficacy and safety of Qiseng® based on extract of American ginseng combined with vitamin C from extract of Camu Camu berries

Eligibility Criteria

Inclusion Criteria: * Patients with localized breast or gynecological cancer treated as curative adjuvant and/or neoadjuvant chemotherapy and/or adjuvant radiotherapy. These treatments must have been completed within 6 months of inclusion. * Patient reporting a chronic, stable fatigue state at investigator assessment, defined as a fatigue score ≥ 4 on the visual analog scale rated up to 10, experienced for at least one month * Maintenance therapy with hormone therapy or other maintenance therapy (trastuzumab, bevacizumab…) is allowed before and/or during the study (except for pembrolizumab, abemaciclib and PARP inhibitors, which are not authorized) * Patient 18 years of age or older * Effective contraception in women of childbearing age * Patient affiliated to a social security plan * Signed informed consent Exclusion Criteria: * Other identified causes of fatigue (anemia of grade \> 2, underlying chronic disease known to be associated with fatigue) * Ongoing chemotherapy (patients

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