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Recruiting Phase 3 NCT03083184

NCT03083184 Evaluation of the Efficacy of an inTerdialytic "Ethanol 40% v/v - enoxapaRin 1000 U/mL" Lock solutioN to Prevent Tunnelled Catheter Infections in Chronic Hemodialysis Patients

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Clinical Trial Summary
NCT ID NCT03083184
Status Recruiting
Phase Phase 3
Sponsor University Hospital, Clermont-Ferrand
Condition Tunnelled Hemodialysis Catheter Infection
Study Type INTERVENTIONAL
Enrollment 400 participants
Start Date 2018-02-09
Primary Completion 2026-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Ethanolenoxaparin

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 3 trials are large pivotal studies comparing the treatment to current standard of care or placebo. Your participation directly contributes to the evidence needed for regulatory approval.

This trial targets 400 participants in total. It began in 2018-02-09 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to assessed the efficacy of a combined solution of ethanol (4%) and low molecular weight heparins LMWH in preventing tunnelled dialysis catheter infection in chronic hemodialysis patients

Eligibility Criteria

Inclusion Criteria: * end-stage renal disease * chronic hemodialysis/hemodiafiltration at least three times a week * functional TC inserted for at least two weeks * Social security cover * Written informed consent Exclusion Criteria: \-

Contact & Investigator

Central Contact

Patrick LACARIN

✉ placarin@chu-clermontferrand.fr

📞 04 73 75 10 81

Principal Investigator

Julien ANIORT

PRINCIPAL INVESTIGATOR

University Hospital, Clermont-Ferrand

Frequently Asked Questions

Who can join the NCT03083184 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Tunnelled Hemodialysis Catheter Infection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT03083184 trial and what does that mean for participants?

Phase 3 trials are large-scale studies comparing the new treatment to existing standards of care or a placebo. They provide the evidence needed for regulatory approval. This trial targets 400 participants.

Is NCT03083184 currently recruiting?

Yes, NCT03083184 is actively recruiting participants. Contact the research team at placarin@chu-clermontferrand.fr for enrollment information.

Where is the NCT03083184 trial being conducted?

This trial is being conducted at Clermont-Ferrand, France.

Who is sponsoring the NCT03083184 clinical trial?

NCT03083184 is sponsored by University Hospital, Clermont-Ferrand. The principal investigator is Julien ANIORT at University Hospital, Clermont-Ferrand. The trial plans to enroll 400 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology