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Recruiting NCT05996497

NCT05996497 Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 Years

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Clinical Trial Summary
NCT ID NCT05996497
Status Recruiting
Phase
Sponsor Institut Pasteur
Condition Dyslexia
Study Type INTERVENTIONAL
Enrollment 160 participants
Start Date 2023-10-05
Primary Completion 2026-01-01

Trial Parameters

Condition Dyslexia
Sponsor Institut Pasteur
Study Type INTERVENTIONAL
Phase N/A
Enrollment 160
Sex ALL
Min Age 7 Years
Max Age 9 Years
Start Date 2023-10-05
Completion 2026-01-01
Interventions
behavioral measuresElectrophysiological measuresTraining 1

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Brief Summary

Studies of dyslexia have shown altered oscillatory activity in the low gamma band (\~25-35 Hz) in the left auditory cortex. Neural oscillations around 30 Hz constitute the basic sampling rate of speech, from which the ability to form specific phonemic categories on which reading learning is based is derived. An alteration of the oscillatory activity at 30 Hz could therefore influence the ability of children to learn to read, and explain the reading deficit observed in children with a specific written language disorder. The objective of our study is to determine whether intensive rhythmic auditory stimulation applied during 30 sessions of 15 minutes spread over 6 weeks (5 sessions per week) can correct neural oscillations in the gamma-low band, allowing an improvement of phonemic categorization abilities, and thus the reading abilities of dyslexic readers aged 7 to 9 years. The long-term objective of this study is to test the therapeutic potential of auditory stimulation with speech rhythms for the treatment of reading disorders.

Eligibility Criteria

Inclusion Criteria: * between 7 and 9 years old * in regular schooling * have a diagnosis of dyslexia * have a non-verbal intelligence assessment within the norm. Inclusion assessments must show a major reading disability without associated cognitive deficits. * be equipped with a PC at home * have given their assent and whose parents/legal guardians have given their oral consent Exclusion Criteria: * have any other diagnosis of language impairment * have a neurological disorder (visual, auditory, executive) * have an associated psychiatric disorder * have a developmental delay.

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