NCT07441447 Evaluation of Muscle Strength and Muscle Mass in Patients With Inflammatory Bowel Disease
| NCT ID | NCT07441447 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sakarya University |
| Condition | Crohn Disease (CD) |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-11-10 |
| Primary Completion | 2026-11-10 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2025-11-10 with a primary completion date of 2026-11-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective observational study aims to evaluate the validity of ultrasonographic muscle measurements in patients with inflammatory bowel disease (IBD). Sarcopenia is commonly assessed using computed tomography (CT)-based skeletal muscle area measurements at the L3 vertebral level, which are considered a gold standard method. However, CT is not always feasible due to radiation exposure and accessibility limitations. In this study, muscle strength will be assessed using handgrip dynamometry, and muscle mass will be evaluated using ultrasonography of selected skeletal muscles. In patients with available recent abdominal CT imaging, L3 skeletal muscle area will be recorded. The primary objective is to compare ultrasonographic muscle measurements with CT-based assessments and to evaluate the agreement between these methods. This study aims to determine whether ultrasonography can serve as a practical and reliable alternative tool for muscle mass evaluation in patients with IBD.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years * Established diagnosis of inflammatory bowel disease (ICD-10: K50.\* Crohn's disease, K51.\* ulcerative colitis) * Ability to provide written informed consent * Ability to undergo ultrasonographic muscle assessment and handgrip strength testing * Availability of an abdominal computed tomography (CT) scan performed within the previous 6 months Exclusion Criteria: * Known neuromuscular disorders or primary muscle diseases * Major orthopedic conditions affecting muscle strength assessment * Pregnancy * Abdominal wall defects or conditions interfering with ultrasound assessment * Incomplete clinical or imaging data * Any condition preventing reliable ultrasound or handgrip measurement
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07441447 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Crohn Disease (CD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07441447 currently recruiting?
Yes, NCT07441447 is actively recruiting participants. Contact the research team at yunusgunegul@sakarya.edu.tr for enrollment information.
Where is the NCT07441447 trial being conducted?
This trial is being conducted at Sakarya, Turkey (Türkiye).
Who is sponsoring the NCT07441447 clinical trial?
NCT07441447 is sponsored by Sakarya University. The trial plans to enroll 100 participants.