NCT06945549 Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging
| NCT ID | NCT06945549 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University |
| Condition | Inflammatory Bowel Disease (IBD) |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-04-25 |
| Primary Completion | 2027-12-31 |
Trial Parameters
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Brief Summary
The goal of this observational study is to evaluate the role and effect of 18F-FAPI PET imaging in the identification of intestinal lesions and the assessment of disease activity in inflammatory bowel disease. The main question it aims to answer is: Can 18F-FAPI PET imaging effectively identify intestinal lesions in inflammatory bowel disease and accurately assess disease activity? Colonoscopy, enhanced abdominal CT, and 18F-FAPI intestinal imaging were completed within 1 week, and major adverse outcomes (MAO) were followed up 12 months after enrollment. Last updated on March 25, 2025
Eligibility Criteria
Inclusion Criteria: * Patients diagnosed with IBD according to clinical, imaging, endoscopic, and histopathological criteria; * Patients ≥18 years old; * 18F-FAPI PET/CT intestinal imaging, conventional endoscopic and enhanced CT were performed within 1 week; * Intestinal segment matching was evaluated by endoscopy and imaging; * Patients voluntarily participate and sign informed consent. Exclusion Criteria: * Pregnant or lactating patients; * Imaging images are of poor quality and cannot be used for diagnosis and evaluation; * Patients with contraindications for endoscopic or CT examination.