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Recruiting Phase 2 NCT07192133

NCT07192133 Evaluation of CT-XPI

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Clinical Trial Summary
NCT ID NCT07192133
Status Recruiting
Phase Phase 2
Sponsor University of Wisconsin, Madison
Condition CT Scan
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2026-01-26
Primary Completion 2026-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
CT scan

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 30 participants in total. It began in 2026-01-26 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to learn if a new computed tomography (CT) lung perfusion imaging method is as effective as standard of care (SOC) CT imaging. The main question it aims to answer is: * Does the new contrast-free method provide more information about lung perfusion than SOC? Participants will undergo a 30 minute chest CT.

Eligibility Criteria

Inclusion Criteria: * Age 18 years or older * Able to sign and date the informed consent form * Will undergo a clinically-indicated CT exam of the head, neck, chest, abdomen, pelvis, or extremities Exclusion Criteria: * Pregnant or lactating * In need of urgent or emergent care * Have any conditions that, in the opinion of the PI or designee, would interfere with the evaluation of the results or constitute a health hazard for the participant

Contact & Investigator

Central Contact

Radiology Studies

✉ radstudy@uwhealth.org

📞 608-282-8349

Principal Investigator

Matthew Smith, MD, PhD

PRINCIPAL INVESTIGATOR

University of Wisconsin, Madison

Frequently Asked Questions

Who can join the NCT07192133 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying CT Scan. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07192133 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07192133 currently recruiting?

Yes, NCT07192133 is actively recruiting participants. Contact the research team at radstudy@uwhealth.org for enrollment information.

Where is the NCT07192133 trial being conducted?

This trial is being conducted at Madison, United States.

Who is sponsoring the NCT07192133 clinical trial?

NCT07192133 is sponsored by University of Wisconsin, Madison. The principal investigator is Matthew Smith, MD, PhD at University of Wisconsin, Madison. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology