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Recruiting NCT07283042

NCT07283042 Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta Spectrum

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Clinical Trial Summary
NCT ID NCT07283042
Status Recruiting
Phase
Sponsor University of California, Los Angeles
Condition Placenta Accreta
Study Type OBSERVATIONAL
Enrollment 60 participants
Start Date 2025-12-01
Primary Completion 2027-12-31

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age 55 Years
Study Type OBSERVATIONAL
Interventions
Total HysterectomyModified subtotal hysterectomyOne-Step Conservative Surgery

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 60 participants in total. It began in 2025-12-01 with a primary completion date of 2027-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study evaluates the clinical implementation of intra-operative topographic classification system for PAS. In addition to a standard of care risk stratification prenatal ultrasound for patients with a risk of PAS, this study adds an additional intraoperative surgical staging protocol to validate the classification system, improve surgical approach, and significantly clinical outcomes of pregnant people with an a prior risk of PAS. The study will involve pregnant patients with PAS risk factor, include data collection spanning prenatal assessment, intraoperative classification, surgical technique implementation and postoperative analysis. The anticipated study duration is approximately 36-48 months.

Eligibility Criteria

Inclusion Criteria: * Pregnant people suspected of having PAS based on ultrasound findings or clinical risk factors * Patients undergoing planned surgical intervention for PAS, including a planned cesarean * Individuals who provide informed consent to participate in the study * Patients with at least one prenatal assessment before surgery * Expected age range: 18-55 * Patient has agreed to conservative management approach as part of standard of care if feasible intraoperatively Exclusion Criteria: * Patients who decline participation or withdraw consent * Those with contraindications to the planned surgical procedure

Contact & Investigator

Central Contact

Dana Levin-Lopez, MPH

✉ dlevinlopez@mednet.ucla.edu

📞 310-794-8893

Principal Investigator

Yalda Afshar, MD, PhD

PRINCIPAL INVESTIGATOR

University of California, Los Angeles

Frequently Asked Questions

Who can join the NCT07283042 clinical trial?

This trial is open to female participants only, aged 18 Years or older, up to 55 Years, studying Placenta Accreta. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07283042 currently recruiting?

Yes, NCT07283042 is actively recruiting participants. Contact the research team at dlevinlopez@mednet.ucla.edu for enrollment information.

Where is the NCT07283042 trial being conducted?

This trial is being conducted at Los Angeles, United States.

Who is sponsoring the NCT07283042 clinical trial?

NCT07283042 is sponsored by University of California, Los Angeles. The principal investigator is Yalda Afshar, MD, PhD at University of California, Los Angeles. The trial plans to enroll 60 participants.

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