NCT07666100 Evaluation of Adverse Effects Related to Prescribed Medications in a Periodontology Clinic
| NCT ID | NCT07666100 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cumhuriyet University |
| Condition | Having a Periodontal Prescription |
| Study Type | OBSERVATIONAL |
| Enrollment | 571 participants |
| Start Date | 2026-03-30 |
| Primary Completion | 2027-07-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 571 participants in total. It began in 2026-03-30 with a primary completion date of 2027-07-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Various pharmacological treatment approaches, primarily antibiotics, analgesics, and antiseptic agents, are frequently used in the treatment of periodontal diseases. While these drugs are important for the clinical effectiveness of periodontal treatment, drug-related side effects can negatively impact patient compliance, quality of life, and overall patient safety, and in some cases, may lead to premature termination of treatment. Early identification of drug-related side effects, assessment of causality, and classification of severity form the basis of pharmacovigilance practices. In this context, the Adverse Event Reporting System (FAERS), run by the United States Food and Drug Administration (FDA), is an important data source for detecting drug-related side effects and presenting safety signals. Large databases like FAERS draw attention to potential drug-related side effects and provide valuable information on drug safety. However, this data is largely based on patient/user or physician feedback, and these systems are insufficient to assess the true frequency, clinical severity, and impact on patients' quality of life of side effects. Side effects related to medications prescribed in periodontology clinics are often considered mild or transient, thus limiting systematic feedback based on real-life data. Therefore, systematic and patient-centered clinical studies using standard algorithms and scales based on real-life data are needed. This study aims to determine the frequency of side effects related to medications prescribed in a periodontology clinic over an 18-month period and to evaluate them according to gender and age. As a secondary aim, it aims to evaluate the causal relationship of these side effects with the medications, their clinical severity, and their impact on patients' quality of life related to oral health using a holistic approach. This will ensure that not only the presence of side effects but also clinical and patient-centered outcomes are presented in an objective, standardized, and reproducible manner.
Eligibility Criteria
Inclusion Criteria: Being 16 years of age or older * Receiving treatment at a periodontology clinic • Having been prescribed at least one pharmacological agent * Volunteering to participate in the study and providing informed consent Exclusion Criteria: * Having a cognitive problem that would prevent the evaluation of side effects related to drug use * Patients who did not come for evaluation during the follow-up period or for whom sufficient follow-up data could not be obtained * Patients who provided incomplete, inconsistent or unreliable data regarding side effect evaluation
Frequently Asked Questions
Who can join the NCT07666100 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, studying Having a Periodontal Prescription. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07666100 currently recruiting?
Yes, NCT07666100 is actively recruiting participants. Visit ClinicalTrials.gov or contact Cumhuriyet University to inquire about joining.
Where is the NCT07666100 trial being conducted?
This trial is being conducted at Sivas, Turkey (Türkiye).
Who is sponsoring the NCT07666100 clinical trial?
NCT07666100 is sponsored by Cumhuriyet University. The trial plans to enroll 571 participants.