NCT07415733 Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
| NCT ID | NCT07415733 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Unilever R&D |
| Condition | Gingival Inflammation |
| Study Type | INTERVENTIONAL |
| Enrollment | 150 participants |
| Start Date | 2026-02-27 |
| Primary Completion | 2026-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 150 participants in total. It began in 2026-02-27 with a primary completion date of 2026-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13 weeks.
Eligibility Criteria
Inclusion Criteria: * Participants need to be competent i.e., able to understand what is to take place and able to provide a free decision on agreeing to the activity/taking part in the study on this. * Participants must be able to read and understand study instructions and any other relevant study documents. * Have at least 20 natural teeth without subgingival calculus, including 5 assessable teeth (excluding 3rd molars) in each quadrant. * Have a mean whole mouth BOP ≥ 10% at screening. * Willing to follow the lifestyle and dietary restrictions as detailed in the Information Sheet for study. Exclusion Criteria: * Be pregnant or breastfeeding. * Participants who participated in gum health study within 3 months prior to screening. * Current participation in any other cosmetic studies, any dental clinical studies or clinical trials. * Participants who have used any gum health products in the 4 weeks prior to screening. * Obvious signs of untreated caries or significant periodontal disease, which in the opinion of the study dentist, will affect either the scientific validity of the study or if the participant to take part in the study would affect their wellbeing. * Have more than three sites with a probing pocket depth (PPD) of ≥ 5 mm. * Full or partial dentures wearers. * Current orthodontic treatment. * Smokers or those who have a recent smoking history, including e-cigarettes. * Diabetics. * Have had a dental prophylaxis in the month prior to enrolment or have one scheduled prior to the end of the study. * Medical condition and/or regular use of any medication which might affect the outcome of the study, as determined by the study dentist, principally a course of anti-inflammatory, antimicrobial or statin drugs within 4 weeks of screening. * Taking dietary supplements (e.g. multivitamins, antioxidants, fish oils, etc.). * Known allergy to any ingredient in study products. * The participant is a Unilever employee or a member of the study team. * Any participant who, in the judgement of the investigator, should not participate in the study.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07415733 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Gingival Inflammation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07415733 currently recruiting?
Yes, NCT07415733 is actively recruiting participants. Contact the research team at bensosulijaya@gmail.com for enrollment information.
Where is the NCT07415733 trial being conducted?
This trial is being conducted at Jakarta Pusat, Indonesia.
Who is sponsoring the NCT07415733 clinical trial?
NCT07415733 is sponsored by Unilever R&D. The trial plans to enroll 150 participants.