NCT07187934 EVALUATION OF A FULLY AUTOMATED AI TOOL FOR EMBRYO RANKING
| NCT ID | NCT07187934 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universitair Ziekenhuis Brussel |
| Condition | Pregnancy |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,325 participants |
| Start Date | 2025-12-11 |
| Primary Completion | 2028-12-11 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,325 participants in total. It began in 2025-12-11 with a primary completion date of 2028-12-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to investigate whether embryo ranking by a fully automated AI tool (iDAScore) results in a similar transfer-to-pregnancy compared to manual embryo ranking by an embryologist. IVF patients who are planned for a freeze-all approach (where all usable embryos are frozen and transferred in later transfer cycles) will be allocated to either the control (ranking by embryologist) or intervention arm (ranking by iDAScore). The frozen embryos will be warmed and transferred one by one, according to their assigned rank. We want to see if the average number of embryo transfers that is needed to achieve a clinical pregnancy (transfer-to-pregnancy) is similar in both groups.
Eligibility Criteria
Inclusion Criteria: * patients undergoing an ICSI/IVF treatment (with donor or own oocytes) that are planned for a 'freeze-all' strategy on day 5 * all types of sperm samples (ejaculated or testicular, fresh or frozen, partner or donor origin) * Minimum 8 follicles (≥ 12 mm) on last follicular measurement before oocyte retrieval * 18 ≤ Age ≤ 42 years * 18 ≤ BMI ≤ 35 kg/m² * Maximum third IVF/ICSI cycle * Participants can be included only once in the trial Exclusion Criteria: * Embassy patients * Use of frozen oocytes * In vitro maturation (IVM) cycles * Pre-implantation genetic Testing (PGT) cycles * Proven untreated intra-uterine pathologies (e.g. Asherman syndrome, adenomysosis) * Endometriosis stage 3/4
Contact & Investigator
Julie Praet, M.D.
PRINCIPAL INVESTIGATOR
Brussels IVF, UZ Brussel
Frequently Asked Questions
Who can join the NCT07187934 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 42 Years, studying Pregnancy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07187934 currently recruiting?
Yes, NCT07187934 is actively recruiting participants. Contact the research team at elsie.nulens@uzbrussel.be for enrollment information.
Where is the NCT07187934 trial being conducted?
This trial is being conducted at Brussels, Belgium.
Who is sponsoring the NCT07187934 clinical trial?
NCT07187934 is sponsored by Universitair Ziekenhuis Brussel. The principal investigator is Julie Praet, M.D. at Brussels IVF, UZ Brussel. The trial plans to enroll 1,325 participants.