NCT07134361 Evaluation by Clinical and Hand Ultrasound in Carpal Tunnel Syndrome
| NCT ID | NCT07134361 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Sao Paulo General Hospital |
| Condition | Carpal Tunnel Syndrome (CTS) |
| Study Type | OBSERVATIONAL |
| Enrollment | 106 participants |
| Start Date | 2025-06-25 |
| Primary Completion | 2028-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 106 participants in total. It began in 2025-06-25 with a primary completion date of 2028-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Carpal Tunnel Syndrome (CTS) is a common condition where pressure on the median nerve in the wrist causes pain, numbness, and weakness in the hand. Surgery to release the carpal tunnel is often performed to relieve these symptoms. This study will evaluate the changes in the median nerve after surgery and how these changes relate to symptom improvement. Investigators will use ultrasound imaging to measure the nerve size before and at three and six months after surgery. Patients will also complete questionnaires about their symptoms and hand function, and undergo tests to assess strength and sensation. The investigator's goal is to determine whether changes observed on ultrasound are associated with the rate of patient recovery. This may help doctors better monitor healing and improve care for people with CTS.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of primary carpal tunnel syndrome (CTS), confirmed by characteristic symptoms, physical examination findings, and a cross-sectional area superior to 10 mm² in the ultrasonography baseline. * Indication for open carpal tunnel release as part of routine clinical care. Exclusion Criteria: * Secondary CTS due to inflammatory arthritis, prior wrist trauma, or space-occupying lesions. * History of previous carpal tunnel release in the affected hand. * Concomitant peripheral neuropathies (e.g., diabetic polyneuropathy) or cervical radiculopathy * Inability to undergo ultrasound assessment
Contact & Investigator
Marcelo Rosa Rezende, MD, PhD,
PRINCIPAL INVESTIGATOR
HOSPITAL DAS CLÍNICAS DA FACULDADE DE MEDICINA DA UNIVERSIDADE DE SÃO PAULO (HCFM/USP)
Frequently Asked Questions
Who can join the NCT07134361 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Carpal Tunnel Syndrome (CTS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07134361 currently recruiting?
Yes, NCT07134361 is actively recruiting participants. Contact the research team at joao.r@hc.fm.usp.br for enrollment information.
Where is the NCT07134361 trial being conducted?
This trial is being conducted at São Paulo, Brazil.
Who is sponsoring the NCT07134361 clinical trial?
NCT07134361 is sponsored by University of Sao Paulo General Hospital. The principal investigator is Marcelo Rosa Rezende, MD, PhD, at HOSPITAL DAS CLÍNICAS DA FACULDADE DE MEDICINA DA UNIVERSIDADE DE SÃO PAULO (HCFM/USP). The trial plans to enroll 106 participants.