NCT07529288 Evaluating Traditional Medicine Syndromes in Male Infertility With Oligoasthenoteratozoospermia
| NCT ID | NCT07529288 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Medicine and Pharmacy at Ho Chi Minh City |
| Condition | Male Infertility With OAT |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2026-01-14 |
| Primary Completion | 2026-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2026-01-14 with a primary completion date of 2026-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to identify and evaluate the characteristics of Traditional Medicine (TM) syndromes in men aged 18 to 60 with male infertility and oligoasthenoteratozoospermia (OAT) syndrome. The main questions it aims to answer are: * What are the common Traditional Medicine syndromes and symptoms associated with male infertility based on Traditional Medicine literature? * What are the specific Traditional Medicine syndromes and symptoms found in men with OAT syndrome at Binh Dan Hospital when analyzed using Latent Tree Models? The research will be conducted in two phases: * Phase 1 (Literature Review): Researchers will collect and analyze Traditional Medicine texts to list the symptoms and syndromes related to male infertility. This phase will help create a standardized clinical survey. * Phase 2 (Clinical Survey): Researchers will recruit 300 male participants with OAT syndrome. * Participants will answer a survey questionnaire about their Traditional Medicine symptoms. * Researchers will apply Latent Tree Models (a mathematical approach) to the collected data to objectively classify the TM syndromes.
Eligibility Criteria
Inclusion Criteria: * Male patients aged between 18 and 60 years. * Diagnosed with male infertility by an andrology specialist according to World Health Organization (WHO) standards. * Semen analysis results meet the diagnostic criteria for Oligoasthenoteratozoospermia (OAT) syndrome. * Voluntary agreement to participate in the research and signed Informed Consent Form. Exclusion Criteria: * Infertility caused by genetic or chromosomal abnormalities, including but not limited to: Klinefelter syndrome, Sandberg mosaic syndrome (46 XY/47 XXY), or XYY syndrome. * Presence of structural abnormalities of the reproductive organs. * Patients with Azoospermia (absence of sperm in the ejaculate) as defined by WHO 2021 standards. * Use of medications affecting spermatogenesis within the last 3 months, including: cannabinoids, hydantoins, valproate, anabolic steroids, cimetidine, colchicine, spironolactone, nitrofurantoin, sulfasalazine, or calcium channel blockers. * Inability to understand or answer survey questions due to physical or mental limitations (e.g., mutism, deafness, intellectual disability, coma, or being on a ventilator in the ICU). * Lack of cooperation during the clinical examination and interview process.
Contact & Investigator
Thi-Bay Nguyen, PhD
STUDY CHAIR
University of Medicine and Pharmacy at Ho Chi Minh City
Frequently Asked Questions
Who can join the NCT07529288 clinical trial?
This trial is open to male participants only, aged 18 Years or older, up to 60 Years, studying Male Infertility With OAT. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07529288 currently recruiting?
Yes, NCT07529288 is actively recruiting participants. Contact the research team at bpmman@uhsvnu.edu.vn for enrollment information.
Where is the NCT07529288 trial being conducted?
This trial is being conducted at Ho Chi Minh City, Vietnam.
Who is sponsoring the NCT07529288 clinical trial?
NCT07529288 is sponsored by University of Medicine and Pharmacy at Ho Chi Minh City. The principal investigator is Thi-Bay Nguyen, PhD at University of Medicine and Pharmacy at Ho Chi Minh City. The trial plans to enroll 300 participants.