NCT07402681 Evaluating Symptom Variations and Observing Longitudinal Individual Change Effects in TF-CBT
| NCT ID | NCT07402681 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Children's Hospital, Zurich |
| Condition | Post-traumatic Stress Symptoms |
| Study Type | OBSERVATIONAL |
| Enrollment | 21 participants |
| Start Date | 2026-02 |
| Primary Completion | 2027-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 21 participants in total. It began in 2026-02 with a primary completion date of 2027-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to learn about the level of change in post-traumatic stress symptoms in adolescents with traumatic experiences over the course of trauma-focused cognitive behavioral therapy for children and adolescents according to Cohen, Manarinno, \& Deblinger (2017).
Eligibility Criteria
Participants will be included if: 1. they are between 12 and 18 years of age; 2. they have been exposed to at least one or more traumatic event(s) according to the DSM-5 A criteria after the age of 3 years and dating back at least 1 months (with regard to the ability of patients to remember the event(s) and to the high spontaneous remissions of PTSS in the first month after a traumatic event); 3. they exhibit high severity of DSM-5 PTSS as indicated by a total symptom score of ≥25 assessed with the Child and Adolescent Trauma Screen 2 (CATS-2); 4. a nonoffending adult caregiver is available for the treatment and willing to participate in weekly treatment sessions (the inclusion of a caregiver is integral to the TF-CBT treatment model); 5. they are willing and able to attend weekly treatment sessions; 6. if their living circumstances are safe and stable to minimize the risk of re-traumatization during the project; 7. they and their caregiver have sufficient command of the German language (i.e., to participate in assessment \[read\] and treatment\[converse\]); 8. they and their caregivers possess a smartphone. 9. they and their caregiver provided written informed consent. Participants will not be included if: 1. they exhibit acute suicidal behavior or have suicidal ideations requiring immediate hospitalization; 2. they have a documented developmental disorder (i.e., autism spectrum disorder) or current psychosis based on adolescent- and caregiver-report and clinical assessment; 3. they exhibit severe substance misuse based on clinical assessment; 4. take part in concurrent psychotherapy during TF-CBT; 5. exhibit severe intellectual disability based on clinical assessment.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07402681 clinical trial?
This trial is open to participants of all sexes, aged 12 Years or older, up to 18 Years, studying Post-traumatic Stress Symptoms. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07402681 currently recruiting?
Yes, NCT07402681 is actively recruiting participants. Contact the research team at lasse.bartels@kispi.uzh.ch for enrollment information.
Where is the NCT07402681 trial being conducted?
This trial is being conducted at Zurich, Switzerland.
Who is sponsoring the NCT07402681 clinical trial?
NCT07402681 is sponsored by University Children's Hospital, Zurich. The trial plans to enroll 21 participants.