NCT06826781 Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise
| NCT ID | NCT06826781 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Spaulding Rehabilitation Hospital |
| Condition | Healthy |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2025-07-23 |
| Primary Completion | 2026-07-23 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2025-07-23 with a primary completion date of 2026-07-23.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are: 1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance? 2. How does the Q-Collar affect brain blood flow during exercise? Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise. Participants will: * Complete two study visits, each 1 to 4 weeks apart. * Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored. * Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.
Eligibility Criteria
Inclusion Criteria: * healthy individuals between the ages of 18 to 30 years old Exclusion Criteria: * History of concussion or other brain injury resulting in loss or alteration in consciousness or other change in cognition within 24 months of study visit * High cardiac risk according to the American College of Sports Medicine (ACSM)11 * Ongoing active treatment with a cardioactive drug * Inability to stand from a seated position unassisted * History of a neurologic disorder or neurosurgery intervention * Pregnancy * Any current, serious, chronic medical or psychiatric disease that in the Principal Investigator's or co-investigator's judgment may interfere with study participation or data integrity * Unable or unwilling to provide informed consent
Contact & Investigator
J. Andrew Taylor, MS, PhD
PRINCIPAL INVESTIGATOR
Harvard Medical School/Spaulding Rehabilitation Hospital
Frequently Asked Questions
Who can join the NCT06826781 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 30 Years, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06826781 currently recruiting?
Yes, NCT06826781 is actively recruiting participants. Contact the research team at jandrew_taylor@hms.harvard.edu for enrollment information.
Where is the NCT06826781 trial being conducted?
This trial is being conducted at Cambridge, United States.
Who is sponsoring the NCT06826781 clinical trial?
NCT06826781 is sponsored by Spaulding Rehabilitation Hospital. The principal investigator is J. Andrew Taylor, MS, PhD at Harvard Medical School/Spaulding Rehabilitation Hospital. The trial plans to enroll 20 participants.