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Recruiting Phase 2 NCT06664125

NCT06664125 Evaluate the Efficacy and Safety of JMKX003002 in End-Stage Renal Disease Patients on Hemodialysis with Hyperphosphatemia

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Clinical Trial Summary
NCT ID NCT06664125
Status Recruiting
Phase Phase 2
Sponsor Jemincare
Condition Hyperphosphatemia
Study Type INTERVENTIONAL
Enrollment 50 participants
Start Date 2024-12-30
Primary Completion 2025-06-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
JMKX003002 will be administered orallySevelamer carbonate

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 50 participants in total. It began in 2024-12-30 with a primary completion date of 2025-06-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

A Phase 2a, Multicenter, Randomized, Open-label, Active Drug-controlled Trial to Evaluate the Efficacy and Safety of JMKX003002 in End-Stage Renal Disease Patients on Hemodialysis with Hyperphosphatemia

Eligibility Criteria

Inclusion Criteria: 1. Able to understand the procedures of this trial and provide written informed consent voluntarily; 2. Age ≥ 18 years, male or female; 3. On a stable hemodialysis regimen at a frequency of two or three times per week for at least 12 weeks prior to the screening visit; 4. Serum phosphorus within the trial-required range. Exclusion Criteria: 1. Any history of inflammatory bowel disease or diarrheal irritable bowel syndrome; 2. Pregnant or breastfeeding; 3. Any history of a parathyroid intervention; 4. Diarrhea or loose stools occurred within 1 week prior to randomization.

Contact & Investigator

Central Contact

Jing Xu

✉ xujing2@jemincare.com

📞 0086-020-87755766

Frequently Asked Questions

Who can join the NCT06664125 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Hyperphosphatemia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06664125 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT06664125 currently recruiting?

Yes, NCT06664125 is actively recruiting participants. Contact the research team at xujing2@jemincare.com for enrollment information.

Where is the NCT06664125 trial being conducted?

This trial is being conducted at Guangzhou, China, Guangzhou, China.

Who is sponsoring the NCT06664125 clinical trial?

NCT06664125 is sponsored by Jemincare. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology