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Recruiting NCT06223672

Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study

Trial Parameters

Condition Cognitive Decline
Sponsor Ohio State University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 88
Sex ALL
Min Age 40 Years
Max Age 75 Years
Start Date 2024-02-07
Completion 2025-12-31
Interventions
WalnutsSimply White Diary-free chocolate bar

Brief Summary

The proposed research is a randomized crossover trial designed to assess changes in postprandial cognitive function and the gut-brain axis in adults with subjective cognitive complaints who consume 1 study snack per day for 1 week.

Eligibility Criteria

Inclusion Criteria: * Subjective cognitive impairment * BMI ≥30 kg/m2 * HbA1C \<6.5% Exclusion Criteria: * Diagnosis og cognitive impairment or dementia * Montreal Cognitive Assessment (MoCA) score of \<26 * Current or previous diagnosis of Diabetes or use of diabetes medications * Current diagnosis of or current treatment of cancer other than non-melanoma skin cancer * Gastrointestinal diseases or disorders (including pancreatic and gastric bypass surgery) where consumption of the study foods would be contraindication or where the disease or disorder could negatively affect nutrient absorption and/or would prevent participants from tolerating the study foods * Hyperthyroidism diagnosis * Food Allergy or intolerances * Any dietary restriction where consumption of the study foods, study meals/snack or meal challenge or any ingredient would be contraindicated * Use of some oil supplements in the past 4 weeks prior to enrolling * Pregnancy and lactation * Inability to access veins for ven

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