NCT06866028 Enhancing Emotion Regulation Through Functional Near-infrared Spectroscopy (fNIRS)-Informed Real-time Neurofeedback
| NCT ID | NCT06866028 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Electronic Science and Technology of China |
| Condition | Neurofeedback |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-08-08 |
| Primary Completion | 2026-08-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2024-08-08 with a primary completion date of 2026-08-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The present study aims to employ real-time functional near-infrared spectroscopy (fNIRS) neurofeedback training in combination with cognitive reappraisal strategies for regulating negative emotions in healthy individuals. Participants will complete: * Cognitive reappraisal training with either real neurofeedback or sham feedback. * Questionnaires at pre- and post- training timepoints * A cold-pressor test at the end of the training It is hypothesized that combining real-time fNIRS neurofeedback and cognitive reappraisal training will enhance emotion regulation in healthy individuals: 1. Increased neural activity in the prefrontal cortex (PFC) region of the brain will be significantly higher in the real neurofeedback group after training compared to the sham feedback group. 2. Real-time fNIRS-guided upregulation of the PFC will enhance emotion regulation during exposure to negative stimuli/scenes across the training runs. 3. The effects of fNIRS neurofeedback training will extend to influence emotion regulation in a cold-pressor test administered post-training, wherein individuals in the real neurofeedback group demonstrate better regulation of stress and pain induced by the task.
Eligibility Criteria
Inclusion Criteria: * Normal/corrected-to-normal vision * Right-handed * Below the cut-off for clinically-significant levels of depression (below 29) indicated by the Beck Depression Inventory (BDI-II; Beck et al., 1996) Exclusion Criteria: * Current/history of mental health conditions * Current/history of chronic pain * The following conditions: Cardiovascular disorder, Raynaud's phenomenon, fainting, seizure, wounds on the hand/arm * Frequent use of alcohol/nicotine
Frequently Asked Questions
Who can join the NCT06866028 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 30 Years, studying Neurofeedback. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06866028 currently recruiting?
Yes, NCT06866028 is actively recruiting participants. Visit ClinicalTrials.gov or contact University of Electronic Science and Technology of China to inquire about joining.
Where is the NCT06866028 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT06866028 clinical trial?
NCT06866028 is sponsored by University of Electronic Science and Technology of China. The trial plans to enroll 50 participants.