Endovascular Treatment for Mild Ischemic Stroke Due to Acute Large Vessel Occlusion in the Anterior Circulation
Trial Parameters
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Brief Summary
Explore the effectiveness and safety of emergency endovascular treatment in patients with mild ischemic stroke due to acute large vessel occlusion in the anterior circulation, identified through perfusion imaging.
Eligibility Criteria
Inclusion Criteria: 1. Age 18-80 years old; 2. Symptoms onset or last known well to randomization is within 24 hours. 3. Clinical diagnosis of acute ischemic stroke due to anterior circulation intracranial large vessel occlusion (LVO) (including intracranial internal carotid artery \[ICA\], middle cerebral artery \[MCA\] M1 segment, MCA M2 segment, with or without ipsilateral extracranial ICA occlusion) confirmed on Computerized tomography angiography (CTA) or Magnetic resonance imaging angiography (MRA) ; 4. Baseline NIHSS score \<6 before randomization (including cases with NIHSS ≥6 at onset but improves before randomization); 5. ASPECTS score ≥6 based on Non-contrast CT (NCCT) before randomization; Exclusion Criteria: 1. Premorbid Rankin Scale (mRS) score ≥ 1; 2. Known allergy to iodine, heparin, anaesthesia, or other definite contraindication to receiving endovascular treatment (EVT) procedure; 3. Patient has severe or fatal co-morbidities that could interfere with outcome assessme