NCT05150483 EndotyPIng PreHospitAl de Novo Acute hYpoxemic Respiratory Failure
| NCT ID | NCT05150483 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Evangelismos Hospital |
| Condition | Acute Hypoxemic Respiratory Failure |
| Study Type | OBSERVATIONAL |
| Enrollment | 250 participants |
| Start Date | 2021-12-10 |
| Primary Completion | 2026-03-25 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 250 participants in total. It began in 2021-12-10 with a primary completion date of 2026-03-25.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
We attempt to perform dynamic endotyping of critically ill patients presenting in the emergency department with de novo acute hypoxemic respiratory failure (AHRF). We also attempt to identify what clinical, radiological, physiological and biological variables collected early in the course of AHRF correlate with subsequent mortality and/or persistent severe hypoxemia.
Eligibility Criteria
Inclusion Criteria: * Adult patients (aged \>18 years) presenting in the emergency department * De novo acute hypoxemic respiratory failure (requiring oxygen flow rate of 5 liters per minute or more to maintain SpO2 of 90% or more) Exclusion Criteria: * Age \<18 years * Not admitted to the hospital * Postoperative acute respiratory failure (within one week from surgery) * Chronic hypoxemic respiratory failure (requiring long term oxygen therapy at home) * Hypercapnic respiratory failure * Transferred from another hospital or facility * Pregnant women * Admitted to the hospital purely to facilitate comfort care * Lack of informed consent
Contact & Investigator
Ilias I. Siempos, MD, DSc
PRINCIPAL INVESTIGATOR
Evangelismos Hospital
Frequently Asked Questions
Who can join the NCT05150483 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Hypoxemic Respiratory Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05150483 currently recruiting?
Yes, NCT05150483 is actively recruiting participants. Contact the research team at helenapapoutsi@gmail.com for enrollment information.
Where is the NCT05150483 trial being conducted?
This trial is being conducted at Athens, Greece.
Who is sponsoring the NCT05150483 clinical trial?
NCT05150483 is sponsored by Evangelismos Hospital. The principal investigator is Ilias I. Siempos, MD, DSc at Evangelismos Hospital. The trial plans to enroll 250 participants.