NCT07130123 Endotracheal Suctionning During Positive Pressure Extubation in ICU
| NCT ID | NCT07130123 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Régional d'Orléans |
| Condition | Mechanical Ventilation With Oral Intubation |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2025-10-03 |
| Primary Completion | 2027-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2025-10-03 with a primary completion date of 2027-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this clinical trial is to evaluate endotracheal suctioning during positive pressure extubation in mechanically ventilated adult patients (over 18 years old) in the intensive care unit (ICU). The main question it aims to answer is whether the intervention improves the respiratory oxygenation index (ROX) three hours after extubation compared to no endotracheal suction during positive pressure extubation. Participants will only need to be extubated by the nursing team in the ICU. Follow-up will consist of evaluating respiratory rate, pulse oximetry and inspired oxygen fraction for three hours following extubation.
Eligibility Criteria
Inclusion Criteria: * Adult patient * Intubated for more than 48 hours * Patient for whom extubation is prescribed by the patient's physician Exclusion Criteria: * Headboard restriction\>30°. * Decision to limit active treatment in advance of reintubation * Protected person (under guardianship or curatorship) * Person under court protection * Persons deprived of liberty * Persons not affiliated to a social security scheme * Pregnant or breast-feeding woman * No co-inclusion with a study whose period of interest is follow-up within 3 hours of extubation.
Contact & Investigator
Cécile FOSSAT
PRINCIPAL INVESTIGATOR
Centre Hospitalier Universitaire d'Orléans
Frequently Asked Questions
Who can join the NCT07130123 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Mechanical Ventilation With Oral Intubation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07130123 currently recruiting?
Yes, NCT07130123 is actively recruiting participants. Contact the research team at fanny.louat@chu-orleans.fr for enrollment information.
Where is the NCT07130123 trial being conducted?
This trial is being conducted at Orléans, France.
Who is sponsoring the NCT07130123 clinical trial?
NCT07130123 is sponsored by Centre Hospitalier Régional d'Orléans. The principal investigator is Cécile FOSSAT at Centre Hospitalier Universitaire d'Orléans. The trial plans to enroll 120 participants.