NCT07604194 Embolosclerotherapy Versus Deep Dorsal Vein Revascularization in Venogenic Erectile Dysfunction
| NCT ID | NCT07604194 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mansoura University Hospital |
| Condition | Erectile Dysfunction Due to Venous Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-06-20 |
| Primary Completion | 2027-05-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2026-06-20 with a primary completion date of 2027-05-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Venous leakage is one of the causes of erectile dysfunction and can be managed using different treatment modalities, including surgical ligation and percutaneous embolization. This randomized clinical trial aims to evaluate and compare the efficacy, durability, safety, side effects, and complications of two treatment procedures-embolosclerotherapy of the periprostatic plexus and deep dorsal vein revascularization-in the management of erectile dysfunction caused by venous leak.
Eligibility Criteria
Inclusion Criteria: * Cases with ED reporting difficulty in attaining or maintaining erection for at least 6 months. * All participants were sexually active, in a stable and heterosexual partnership, living with their sexual partner for at least the past one year, and have only one sexual partner. * The frequency of trying sexual intercourse was ≥1/week. * Unsatisfactory response to PDE5i medication. * All cases suffered venogenic erectile dysfunction diagnosed by color flow Doppler sonography before and after intracavernous injection of vasoactive drugs or Dynamic infusion cavernosometry-cavernosography (selected cases), which indicated veno-occlusive dysfunction. Exclusion Criteria: * Refusal to participate. * Major psychological or psychiatric disorders. * Non-vascular causes of ED including penile anatomic defects, any related neurological etiology or spinal cord injury, hypogonadism and hormonal disturbances. * History of previous venous surgery, suspected or proven deep venous thrombosis, history of Deep Vein Thrombosis.
Contact & Investigator
Mosaad A Soliman, MD, PhD
PRINCIPAL INVESTIGATOR
vascular surgery department, faculty of medicine, mansoura university
Frequently Asked Questions
Who can join the NCT07604194 clinical trial?
This trial is open to male participants only, aged 40 Years or older, up to 80 Years, studying Erectile Dysfunction Due to Venous Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07604194 currently recruiting?
Yes, NCT07604194 is actively recruiting participants. Contact the research team at hassan3ash1996@gmail.com for enrollment information.
Where is the NCT07604194 trial being conducted?
This trial is being conducted at Al Mansurah, Egypt.
Who is sponsoring the NCT07604194 clinical trial?
NCT07604194 is sponsored by Mansoura University Hospital. The principal investigator is Mosaad A Soliman, MD, PhD at vascular surgery department, faculty of medicine, mansoura university. The trial plans to enroll 60 participants.