NCT07348705 Electrophysiology-based DBS Programming for PD
| NCT ID | NCT07348705 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Florida |
| Condition | Parkinson's Disease (PD) |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-01-15 |
| Primary Completion | 2027-01-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-01-15 with a primary completion date of 2027-01-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Deep brain stimulation (DBS) effectively alleviates motor symptoms in Parkinson's disease (PD). However, current programming is manual and time-consuming. This study will evaluate physiology-based programming using local field potentials (LFPs) to identify optimal stimulation parameters. Specifically, DBS contact selection based on beta power and a broad-band approach will be compared with conventional clinician-based programming.
Eligibility Criteria
Inclusion Criteria: * Patients with a diagnosis of idiopathic PD fulfilling the Movement Disorder Society Clinical Diagnostic Criteria for PD * DBS implantation with the Percept DBS device (Medtronic, USA) for the treatment of motor symptoms * Ability to give informed consent for the study * Willingness to do this study at the time of the initial programming session * Age 21 to 89 years old Exclusion Criteria: * Inability to comply with the study protocol * Atypical Parkinsonism * Any personality or mood symptoms that study personnel believe will interfere with the study requirements
Contact & Investigator
Joshua Wong, MD
PRINCIPAL INVESTIGATOR
University of Florida
Frequently Asked Questions
Who can join the NCT07348705 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 89 Years, studying Parkinson's Disease (PD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07348705 currently recruiting?
Yes, NCT07348705 is actively recruiting participants. Contact the research team at Joshua.Wong@neurology.ufl.edu for enrollment information.
Where is the NCT07348705 trial being conducted?
This trial is being conducted at Gainesville, United States.
Who is sponsoring the NCT07348705 clinical trial?
NCT07348705 is sponsored by University of Florida. The principal investigator is Joshua Wong, MD at University of Florida. The trial plans to enroll 30 participants.
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