NCT06268236 Electro-acupuncture to Treat Disorder of Consciousness
| NCT ID | NCT06268236 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine |
| Condition | Disorder of Consciousness |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-01-01 |
| Primary Completion | 2026-01-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2024-01-01 with a primary completion date of 2026-01-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
With the rapid development of life support technology, more and more people can survive severe brain injury. Some survivors regain consciousness after a period of coma, however, many patients develop prolonged disorders of consciousness (DOC), which poses a therapeutic challenge for clinicians and a heavy burden for their families. The investigators design an Electro-acupuncture to treat disorder of consciousness (AcuDoc) trial with the aim of validating the clinical effect of electroacupuncture in treating DOC and exploring its therapeutic mechanisms by integrating EEG, neuroimaging, evoked potential tests, and behavioral assessments.
Eligibility Criteria
Inclusion Criteria: 1. Age ≥ 18 years; 2. With cerebral damage due to TBI； 3. Diagnosed with UWS or MCS based on at least two CRS-R assessments; 4. From 4 to 16 weeks from the onset of brain injury; 5. Informed consent obtained. Exclusion Criteria: 1. With a history of neurological or psychiatric disorder prior to the brain injury; 2. With uncontrolled seizures or status epilepticus; 3. Unstable vital signs and requiring the use of vasoactive agents; 4. With the use of general anesthetics or central acting sedative; 5. Without intact skin at acupoints or sham points; 6. Concomitant medical illness that would interfere with the outcome assessments and/or follow-up 7. Pregnant patients; 8. Currently participating in other investigational trials; 9. High likelihood of not adhering to the study treatment or the follow-up regimen
Contact & Investigator
Fang Yuan, PhD
STUDY DIRECTOR
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Frequently Asked Questions
Who can join the NCT06268236 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Disorder of Consciousness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06268236 currently recruiting?
Yes, NCT06268236 is actively recruiting participants. Contact the research team at yuanfang@gzucm.edu.cn for enrollment information.
Where is the NCT06268236 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT06268236 clinical trial?
NCT06268236 is sponsored by The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine. The principal investigator is Fang Yuan, PhD at The Second Affiliated Hospital of Guangzhou University of Chinese Medicine. The trial plans to enroll 50 participants.