NCT07669558 Electrical Impedance Tomography-Guided Identification of the Optimal Lateral Position in Postoperative ARDS
| NCT ID | NCT07669558 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ruijin Hospital |
| Condition | Acute Respiratory Distress Syndrome (ARDS) |
| Study Type | INTERVENTIONAL |
| Enrollment | 22 participants |
| Start Date | 2026-06-28 |
| Primary Completion | 2026-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 22 participants in total. It began in 2026-06-28 with a primary completion date of 2026-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective, randomized crossover physiological study evaluates the effects of lateral positioning (left lateral position and right lateral position) versus the supine position on ventilation-perfusion (V/Q) matching in adult postoperative abdominal surgery participants with acute respiratory distress syndrome (ARDS). Bedside electrical impedance tomography (EIT) will be used to quantify regional ventilation and perfusion (perfusion derived from an intravenous tracer bolus administered during a brief breath-hold) and to calculate global "normal V/Q" (normal V/Q, %). Oxygenation, respiratory mechanics (when applicable), and hemodynamics will be recorded concurrently. Feasibility and safety of the positioning protocol will also be assessed.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years * Postoperative abdominal surgery patients admitted to the ICU with ARDS (Berlin definition) * Considered able to tolerate protocolized position changes by the treating team * EIT belt placement and protocol procedures feasible * Informed consent obtained from the patient or legally authorized representative Exclusion Criteria: * Contraindication to lateral positioning (e.g., unstable spine, uncontrolled bleeding, open abdomen, high-risk surgical wound condition) * Severe hemodynamic instability or other conditions making participation unsafe * High risk of airway/vascular line/drain dislodgement not manageable * Pregnancy * Refusal of informed consent * Any other condition deemed inappropriate by investigators
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07669558 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Respiratory Distress Syndrome (ARDS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07669558 currently recruiting?
Yes, NCT07669558 is actively recruiting participants. Contact the research team at ccmzhangrui@foxmail.com for enrollment information.
Where is the NCT07669558 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT07669558 clinical trial?
NCT07669558 is sponsored by Ruijin Hospital. The trial plans to enroll 22 participants.