NCT06914960 Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy
| NCT ID | NCT06914960 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bengu Turemenogullari |
| Condition | Gonarthrosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 66 participants |
| Start Date | 2025-04-15 |
| Primary Completion | 2026-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 66 participants in total. It began in 2025-04-15 with a primary completion date of 2026-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main symptom of knee osteoarthritis, which occurs after damage to the joint cartilage with age, is pain, but this symptom often becomes chronic. Current conservative treatments have moderate effects on chronic knee pain and their use is limited due to the risk of side effects. In addition to pain, patients also experience other symptoms. As a result of the osteoarthritis process, prorioception in the knee is impaired with a decrease in mechanoreceptors, resulting in loss of balance and an increase in the risk of falling.
Eligibility Criteria
Inclusion Criteria: * Age between 30-75 * Chronic knee pain that lasts at least 6 months * Radiographic confirmation of osteoarthritis: Presence of Grade 3 or 4 radiographic changes characterized by significant narrowing in the medial space of the tibiofemoral joint according to the Kellgren-Lawrence classification system * Knee pain \>40 mm when performing one of the two movements that cause the most severe pain (sitting to standing or going up and down stairs) according to 100 mm VAS * 50% reduction in VAS with diagnostic genicular nerve block Exclusion Criteria: * Presence of systemic inflammatory disease such as rheumatoid arthritis * Previous RFA treatment to the knee or hyaluronic acid or steroid injection to the knee within the last 3 months * History of previous knee surgery * Clinically significant structural abnormalities other than osteoarthritis that may lead to chronic knee pain * Having undergone physical therapy to the knee in the last 6 months or a history of knee trauma * Application of other pain treatments * Body-Mass İndex \<18 and \>40 kg/m2 * Pregnancy * Presence of uncontrolled serious illness (cancer, diabetes, etc.), infection, psychiatric disorder, coagulation disorder
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06914960 clinical trial?
This trial is open to participants of all sexes, aged 30 Years or older, up to 75 Years, studying Gonarthrosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06914960 currently recruiting?
Yes, NCT06914960 is actively recruiting participants. Contact the research team at drbenguturemen@gmail.com for enrollment information.
Where is the NCT06914960 trial being conducted?
This trial is being conducted at Ankara, Turkey (Türkiye).
Who is sponsoring the NCT06914960 clinical trial?
NCT06914960 is sponsored by Bengu Turemenogullari. The trial plans to enroll 66 participants.