NCT06987877 Efficacy of Routine Saline Flushing in the Prevention of Nephrostomy Tube Obstructions: A Pilot Study
| NCT ID | NCT06987877 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Brigham and Women's Hospital |
| Condition | Nephrostomy |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2026-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2026-01-01 with a primary completion date of 2026-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators performing this research to study if routine flushing is necessary to prevent obstructions of a nephrostomy tube. This study will evaluate patients that have nephrostomy tube or will have nephrostomy tubes placed as part of their standard clinical care. If participants agree to participate in this study, participants will undergo randomized assignment to either continue to routinely flush the nephrostomy tube with normal saline or not to routinely flush the nephrostomy tube with normal saline. Participantswill be in the study for approximately 3 months if they decide to stay for the whole study.
Eligibility Criteria
Inclusion Criteria: • Age 18-80, with planned nephrostomy tube exchange or new nephrostomy tube placement with ongoing need for a nephrostomy tube. Exclusion Criteria: * Current local infection * History of anaphylaxis to iodinated contrast * Pregnant or intent to become pregnant during the study * Irreversible coagulopathy * Planned for definitive treatment for the clinical indication of the nephrostomy tube prior to 12-week post-intervention. * Planned routine exchange prior to 12 weeks after nephrostomy tube exchange or placement procedure * Complete sensory loss below T10 dermatome.
Contact & Investigator
Yan Epelboym, MD, MPH
PRINCIPAL INVESTIGATOR
MGB
Frequently Asked Questions
Who can join the NCT06987877 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Nephrostomy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06987877 currently recruiting?
Yes, NCT06987877 is actively recruiting participants. Contact the research team at yepelboym@bwh.harvard.edu for enrollment information.
Where is the NCT06987877 trial being conducted?
This trial is being conducted at Boston, United States.
Who is sponsoring the NCT06987877 clinical trial?
NCT06987877 is sponsored by Brigham and Women's Hospital. The principal investigator is Yan Epelboym, MD, MPH at MGB. The trial plans to enroll 20 participants.