NCT06882564 Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.
| NCT ID | NCT06882564 |
| Status | Recruiting |
| Phase | Phase 3 |
| Sponsor | Al-Mustansiriyah University |
| Condition | Halitosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 54 participants |
| Start Date | 2025-01-05 |
| Primary Completion | 2025-04-01 |
Trial Parameters
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Brief Summary
The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah University/College of Dentistry and Wasit University /College of Dentistry. Objectives: * To assess the efficacy of anti-oxidant and anti-inflammatory resveratrol mouthwash in reducing halitosis in undergraduate students with plaque-induced gingivitis patients. * To assess the efficacy of resveratrol mouthwash in reducing p. gingivalis in undergraduate students' patients with oral malodor. * To determine the relation between p.gingivalis and clinical periodontal parameters (plaque index, gingival index, bleeding on probing) among undergraduate students with plaque-induced gingivitis and halitosis.
Eligibility Criteria
Inclusion Criteria: * Organoleptic tongue of scores \> 2 using (0-5scale) (Rosenberg and McCulloch, 1992) * Male and female undergraduate dental students without chemical plaque control measures for at least one weak * Male and female students with halitosis due to gingivitis * The age of students ranges from 20 to 23 years. * No periodontal treatment for at least one month * No systemic disease * No tobacco smoking * The patients must have at least 20 teeth Exclusion Criteria: * Smokers and alcoholics * Patient with periodontitis or pocket depth \> 6mm * Patient with orthodontics appliance * Open carious lesions, pericoronitis, dry socket, and fistula. * Patients with systemic disease and condition * taking medication in the last two weeks * Take garlic, onion, or licorice in the last 24 hours * using oral hygiene products in the last 24 hours * pregnant women * sinusitis, tonsilitis, and upper respiratory tract infection