NCT07083596 Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults
| NCT ID | NCT07083596 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Santo Tomas |
| Condition | Constipation |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-04-22 |
| Primary Completion | 2026-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2026-04-22 with a primary completion date of 2026-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary purpose of this study is to investigate whether the consumption of a probiotic drink (with Lacticaseibacillus paracasei strain Shirota (LcS)) relieves constipation-related symptoms of Filipino adults, specifically its effect on stool consistency, frequency, and duration, and on gastrointestinal discomfort.
Eligibility Criteria
Inclusion Criteria: * Filipino adult male or female aged 18 to 59 years old * Apparently healthy adults with constipation-related symptoms of hard to lumpy stools (Bristol Stool Form Scale 1-2) in 25% or more of defecations in a week * With cold storage at home Exclusion Criteria: 1. Habitual intake of food items containing probiotics and prebiotics as food supplements (previous 3 months, at least three times per week) 2. Constipation due to organic or neurologic origin 3. High fiber intake (\>30 g/day) 4. Pregnant or lactating 5. Allergy to dairy products and/or lactose intolerance 6. Use of laxatives, anticholinergics and medications for constipation or diarrhea within the past three months 7. Use of antibiotics within the past two weeks 8. Presence of chronic diseases such as diabetes mellitus and its complications, cardiovascular diseases, kidney problems 9. GI condition that may interfere with the evaluation of the outcome such as hemorrhoids, intestinal obstruction and inflammatory bowel diseases 10. Recent history of any gastrointestinal surgery 11. Have pre-existing medical conditions like hypo- or hyperthyroidism and congenital abnormalities 12. Participation in another study with test product two months prior the study
Contact & Investigator
Diane S MENDOZA-SARMIENTO, Ph.D in Health Research
PRINCIPAL INVESTIGATOR
University of Santo Tomas
Frequently Asked Questions
Who can join the NCT07083596 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 59 Years, studying Constipation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07083596 currently recruiting?
Yes, NCT07083596 is actively recruiting participants. Contact the research team at dsmendoza@ust.edu.ph for enrollment information.
Where is the NCT07083596 trial being conducted?
This trial is being conducted at Manila, Philippines.
Who is sponsoring the NCT07083596 clinical trial?
NCT07083596 is sponsored by University of Santo Tomas. The principal investigator is Diane S MENDOZA-SARMIENTO, Ph.D in Health Research at University of Santo Tomas. The trial plans to enroll 60 participants.