| NCT ID | NCT07529457 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Wecare Probiotics Co., Ltd. |
| Condition | Constipation |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2026-07-24 |
| Primary Completion | 2027-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2026-07-24 with a primary completion date of 2027-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized, double-blind, placebo-controlled trial will assess the clinical effects of probiotics in adults with functional constipation. Participants will receive probiotics or placebo for 8 weeks. The study will evaluate changes in bowel habits and symptom burden, as well as alterations in host inflammatory status, immune modulation, microbial ecosystem dynamics, neuroendocrine signaling related to the gut-brain axis, and systemic metabolic responses, to characterize the overall physiological impact of probiotic supplementation.
Eligibility Criteria
Inclusion Criteria: 1. Men and women aged between 18 and 65 years; 2. Participants presenting with constipation, characterized by \<3 spontaneous bowel movements per week or BSFS stool types 1-2; 3. Capable of following the study protocol and completing all required assessments; Individuals who have voluntarily signed the informed consent form; 4. No plans for pregnancy from at least 14 days prior to screening through 6 months after the study, with agreement to use reliable contraception methods. Exclusion Criteria: 1. Intake of similar functional products within a short period prior to enrollment that could influence study results; 2. Participants who significantly alter their habitual diet during the trial; 3. Individuals with severe allergic conditions or impaired immune function; 4. Women who are pregnant, lactating, or intending to conceive; 5. Patients with serious underlying diseases affecting major organs or metabolic systems; 6. Antibiotic treatment within 2 weeks before enrollment; 7. Individuals with severe mental or psychological disorders; 8. Non-compliance with study requirements, including improper intake or missed follow-ups; 9. Other subjects considered inappropriate for participation by the investigator.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07529457 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Constipation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07529457 currently recruiting?
Yes, NCT07529457 is actively recruiting participants. Contact the research team at 1959643812@qq.com for enrollment information.
Where is the NCT07529457 trial being conducted?
This trial is being conducted at Suzhou, China.
Who is sponsoring the NCT07529457 clinical trial?
NCT07529457 is sponsored by Wecare Probiotics Co., Ltd.. The trial plans to enroll 70 participants.