NCT07087951 Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)
| NCT ID | NCT07087951 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chang Gung Memorial Hospital |
| Condition | EEG Brain Oscillations |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2025-11-14 |
| Primary Completion | 2028-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2025-11-14 with a primary completion date of 2028-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Animal studies have shown that 40 Hz auditory stimulation alone can improve spatial memory and reduce Aβ deposition. However, human studies using 40 Hz auditory stimulation alone remain limited. Therefore, this study will use a randomized, double-blind, placebo-controlled design to investigate the effects of 40 Hz auditory stimulation on cognitive function, EEG activity, sleep quality, and quality of life in older adults with mild cognitive impairment (MCI) or mild dementia.
Eligibility Criteria
Inclusion Criteria: 1. Age over 60 years old. 2. MMSE≤ 24 3. CDR scores of 0.5 and 1 4. Voluntary to sign the Informed Consent Form. Exclusion Criteria: 1. Diagnosis of other psychiatric or neurological disorders 2. Drug or alcohol addictions. 3. Serious heart, liver or kidney disorders, and visual, auditory or motor impairments interfering with neuropsychological tests. 4. History of clinical stroke, major depressive disorder or dysthymic disorder according to the DSM-5.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07087951 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, studying EEG Brain Oscillations. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07087951 currently recruiting?
Yes, NCT07087951 is actively recruiting participants. Contact the research team at ch.cheng@mail.cgu.edu.tw for enrollment information.
Where is the NCT07087951 trial being conducted?
This trial is being conducted at Taoyuan, Taiwan.
Who is sponsoring the NCT07087951 clinical trial?
NCT07087951 is sponsored by Chang Gung Memorial Hospital. The trial plans to enroll 70 participants.