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Recruiting EARLY_Phase 1 NCT07012486

Efficacy of Dihydroartemisinin for Treating Female Androgenetic Alopecia

Trial Parameters

Condition Androgenetic Alopecia (AGA)
Sponsor Shanghai Zhongshan Hospital
Study Type INTERVENTIONAL
Phase EARLY_Phase 1
Enrollment 30
Sex FEMALE
Min Age 18 Years
Max Age 40 Years
Start Date 2025-06
Completion 2026-05
Interventions
Oral DHA + Topical minoxidil 5%Topical Minoxidil 5%

Brief Summary

The goal of this clinical trial is to learn if dihydroartemisinin (DHA) works to treat Androgenetic Alopecia (AGA) in female adults. The main question it aims to answer is: • Does DHA increase terminal hair follicles in the vertex area. Researchers will compare oral DHA plus topical minoxidil to topical minoxidil alone in female patients with AGA to see if DHA works to alleviate AGA. Participants will: * Receive oral DHA every day plus topical minoxidil or use topical minoxidil alone for 6 months. * Visit the clinic once every month for checkups and tests.

Eligibility Criteria

Inclusion Criteria: * Clinically diagnosed with androgenetic alopecia (AGA) * No pregnancy plans within the next 6 months Exclusion Criteria: * Patients who received systemic medications for hair loss within the past 2 months * Use of topical medication for hair loss within the past 2 weeks * Pregnancy or lactation * Patients with known severe diseases of vital organs (e.g., heart, liver, kidney) or malignancies.

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