NCT07488598 Efficacy of Behavioral Therapy for Chronic Refractory Cough
| NCT ID | NCT07488598 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Assiut University |
| Condition | Chronic Cough |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-03-10 |
| Primary Completion | 2027-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-03-10 with a primary completion date of 2027-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Chronic cough is defined as cough persisting for more than eight weeks. It is a common clinical problem that significantly impairs patients' physical, psychological, and social quality of life. Chronic cough remains a diagnostic and therapeutic challenge despite systematic evaluation and treatment of common etiologies such as asthma, gastroesophageal reflux disease
Eligibility Criteria
Inclusion Criteria: * Eligible participants are adults aged ≥18 years i.e. normal chest radiograph. * participants with chronic cough persisting for more than eight weeks that is refractory to standard medical treatment for common causes of chronic cough, including asthma, gastroesophageal reflux disease . * Participants are required to exhibit clinical features suggestive of laryngeal hyperresponsiveness, such as cough triggered by phonation, laughter, cold air, or irritant exposure, with associated laryngeal symptoms including throat irritation, dysphonia, or frequent throat clearing. Exclusion Criteria: * Patients are excluded if they are current smokers or had ceased smoking within six months * patients have evidence of active pulmonary or cardiac disease, recent respiratory tract infection, recent angiotensin-converting enzyme inhibitor use. * significant structural laryngeal pathology, neurological disorders affecting cough reflex control, or inability to comply with study procedures. * Head \&neck pathology e.g sinusitis, glottal insufficiency or primary muscle tension dysphonia
Contact & Investigator
Eman Sayed Hassan, Professor
STUDY CHAIR
Head of Phoniatric unit,ENT Department,Faculty of Medicine, Assiut University
Frequently Asked Questions
Who can join the NCT07488598 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Chronic Cough. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07488598 currently recruiting?
Yes, NCT07488598 is actively recruiting participants. Contact the research team at mhamedshaaban6@gmail.com for enrollment information.
Where is the NCT07488598 trial being conducted?
This trial is being conducted at Asyut, Egypt.
Who is sponsoring the NCT07488598 clinical trial?
NCT07488598 is sponsored by Assiut University. The principal investigator is Eman Sayed Hassan, Professor at Head of Phoniatric unit,ENT Department,Faculty of Medicine, Assiut University. The trial plans to enroll 30 participants.