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Recruiting NCT06009523

Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation

Trial Parameters

Condition Depression and Suicide
Sponsor Centre Hospitalier Henri Laborit
Study Type INTERVENTIONAL
Phase N/A
Enrollment 50
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-10-26
Completion 2027-09-01
Interventions
Transcranial direct current stimulation

Brief Summary

The main objective of this study is to demonstrate that 15 transcranial direct current stimulation (tDCS) sessions of 30 minutes at 2 mA intensity are effective to reduce suicidal ideation

Eligibility Criteria

Inclusion Criteria: * Age over 18 years * Written informed consent * Diagnosis of recurrent or isolated depressive episode according to DSM IV criteria (A.P.A. 1994). * Stable antidepressant treatment for 3 weeks * MADRS score ≥ 20 * SSI score \> 3 * Subject affiliated to a health insurance system * Woman with effective contraception and agreeing to maintain it throughout the study period. Exclusion Criteria: * Depression with psychotic features Axis I (DSM IV) co-morbid diagnosis of schizophrenia, alcohol and/or other substance dependence (or abuse) (lifetime) * Patient who has already undergone an electroconvulsive therapy course for the current episode and does not respond to this treatment * Patient deprived of liberty * Patient with high suicide risk (item 10 MADRS \> 4) in the absence of hospitalization * Contraindication to tDCS: intracerebral metallic implant (with the exception of dental implants), cardiac pacemaker, active or non-implanted devices in the region of the head, a

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