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Recruiting NCT06389851

Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD

Trial Parameters

Condition NAFLD
Sponsor Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Study Type INTERVENTIONAL
Phase N/A
Enrollment 60
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2024-05-14
Completion 2025-05-20
All Conditions
Interventions
Experimental: Case Group - Tomato-free dietExperimental: Case group - Diet enriched with tomatoes

Brief Summary

The study in question is an interventional study with nutritional intervention. the aim of the study is to evaluate whether a diet enriched with tomatoes can have favorable effects on: * specific aspects associated with NAFLD, such as the degree of hepatic steatosis and fibrosis; * circulating levels of molecules correlated with the degree of generalized and hepatic inflammation and the blood concentrations of metabolic and cardiovascular risk factors associated with abdominal obesity; * intestinal barrier; * body composition; * intestinal microbiota; * symptoms of IBS (irritable bowel syndrome) in patients with NAFLD.

Eligibility Criteria

Inclusion Criteria: * Patients with BMI≤30; * Diagnosis of hepatic steatosis, formulated on the basis of criteria Exclusion Criteria: * Patients with BMI \> 30; * Presence of any pathology that could influence the presence of steatosis apart from the pathologies that represent inclusion criteria; * Pregnancy or breastfeeding; * Serious medical conditions that may compromise participation in the trial; * People following a special diet.

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