← Back to Clinical Trials
Recruiting Phase 2 NCT06446479
Effects of THC on Alcohol Consumption and Neural Correlates of Reward
Trial Parameters
Condition Cannabis Use Disorder
Sponsor University of Colorado, Denver
Study Type INTERVENTIONAL
Phase Phase 2
Enrollment 28
Sex ALL
Min Age 21 Years
Max Age 40 Years
Start Date 2024-07-01
Completion 2026-06-30
Interventions
Dronabinol PillPlacebo
Brief Summary
Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption patterns. The proposed study will explore the effects of oral THC (20mg dronabinol) vs. placebo on neural reward, alcohol self-administration and naturalistic co-use patterns.
Eligibility Criteria
Inclusion Criteria: * Drink alcohol * Use cannabis * Contact site for additional details Exclusion Criteria: * MRI contraindications (implanted metal, weight \> 315 lb, etc.). * Contact site for additional details
Related Trials
NCT06446479
Effects of THC on Alcohol Consumption and Neural Correlates of Reward
View Trial →
NCT06124846
Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adole
View Trial →
NCT05445180
Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric
View Trial →