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Recruiting NCT06323018

Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty.

Trial Parameters

Condition Osteoarthritis, Hip
Sponsor University of Tartu
Study Type INTERVENTIONAL
Phase N/A
Enrollment 200
Sex ALL
Min Age 65 Years
Max Age 90 Years
Start Date 2024-03-20
Completion 2026-03
Interventions
Remote Ischemic PreconditioningSHAM

Brief Summary

Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities. Bone cement implantation syndrome is associated with cemented hip arthroplasty and it has been shown to increase cardiovascular and renal complication and brain damage postoperatively. The aim of this project is to elucidate whether remote-ischemic preconditioning (RIPC) has multi-organ protective effect in cemented hip arthroplasty patients.

Eligibility Criteria

Inclusion Criteria: * age \>65 years * undergoing total hip cemented hip arthroplasty Exclusion Criteria: * previously diagnosed peripheral artery disease on both upper limb * RIPC is contraindicated

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