NCT07694804 Effects of Proprioceptive Neuromuscular Facilitation and Task-Oriented Training on Upper Extremity Function in Children With Spastic Diplegic Cerebral Palsy
| NCT ID | NCT07694804 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ibadat International University, Islamabad |
| Condition | Cerebral Palsy |
| Study Type | INTERVENTIONAL |
| Enrollment | 63 participants |
| Start Date | 2026-02-17 |
| Primary Completion | 2026-07-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 63 participants in total. It began in 2026-02-17 with a primary completion date of 2026-07-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Children with spastic diplegic cerebral palsy often experience upper extremity impairments, including reduced coordination, muscle control, and functional hand use, which limit independence in daily activities. Proprioceptive Neuromuscular Facilitation (PNF) and Task-Oriented Training (TOT) are commonly used rehabilitation approaches to improve motor function; however, evidence comparing their individual and combined effects on upper extremity function remains limited. This randomized controlled trial aims to compare the effects of PNF alone, TOT alone, and a combined PNF plus TOT intervention on upper extremity function in children with spastic diplegic cerebral palsy. Sixty-three children aged 6 to 12 years with Gross Motor Function Classification System (GMFCS) levels I to III will be randomly assigned to one of three intervention groups. Each group will receive supervised 45-minute treatment sessions, three times per week for six weeks. Upper extremity function, functional independence, and joint range of motion will be assessed at baseline, mid-intervention (3 weeks), and post-intervention (6 weeks) using the Melbourne Assessment of Unilateral Upper Limb Function (MA2), Pediatric Evaluation of Disability Inventory-Functional Skills Scale (PEDI-FSS), and goniometric measurements. The findings of this study are expected to provide evidence regarding the most effective rehabilitation approach for improving upper extremity function in children with spastic diplegic cerebral palsy.
Eligibility Criteria
Inclusion Criteria: * Children aged 6 to 12 years. * Clinical diagnosis of spastic diplegic cerebral palsy. * Gross Motor Function Classification System (GMFCS) Levels I-III. * Ability to understand and follow simple verbal instructions. * Medically stable and able to participate in physiotherapy sessions. * Parent or legal guardian willing to provide written informed consent. Exclusion Criteria: * Orthopedic surgery involving the upper or lower extremities within the previous 6 months. * Botulinum toxin injections administered within the previous 6 months. * Severe visual, hearing, or cognitive impairments that would interfere with assessment or treatment. * Uncontrolled epilepsy or other unstable neurological or medical conditions. * Fixed upper extremity contractures or musculoskeletal deformities preventing participation in the intervention. * Participation in another structured upper extremity rehabilitation program during the study period. * Failure to obtain informed consent from a parent or legal guardian.
Contact & Investigator
Dr Zahid Mehmood
PRINCIPAL INVESTIGATOR
Ibadat International University
Frequently Asked Questions
Who can join the NCT07694804 clinical trial?
This trial is open to participants of all sexes, aged 6 Years or older, up to 12 Years, studying Cerebral Palsy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07694804 currently recruiting?
Yes, NCT07694804 is actively recruiting participants. Contact the research team at naumankhan5998@gmail.com for enrollment information.
Where is the NCT07694804 trial being conducted?
This trial is being conducted at Mansehra, Pakistan.
Who is sponsoring the NCT07694804 clinical trial?
NCT07694804 is sponsored by Ibadat International University, Islamabad. The principal investigator is Dr Zahid Mehmood at Ibadat International University. The trial plans to enroll 63 participants.
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