NCT04885322 Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands
| NCT ID | NCT04885322 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, Davis |
| Condition | Healthy |
| Study Type | INTERVENTIONAL |
| Enrollment | 75 participants |
| Start Date | 2021-04-14 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 75 participants in total. It began in 2021-04-14 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to better understand the neural correlates of higher-order cognition, both in the healthy brain and in schizophrenia, and to determine how these mechanisms are modulated by transcranial direct current stimulation (tDCS) at frontal and occipital scalp sites. Testing the effects of tDCS at these scalp sites on cognitive task performance will help us understand the roles of the brain regions corresponding to these sites during higher-order cognitive processing (language comprehension, cognitive control, and related attention and memory processes). Behavioral and electrophysiological (EEG) measures will be used to assess cognitive performance. Our overarching hypothesis is that stimulating prefrontal circuits with tDCS can improve cognitive control performance, and ultimately performance on a range of cognitive tasks, as compared to stimulating a different cortical region (occipital cortex) or using sham stimulation. This study is solely intended as basic research in order to understand brain function in healthy individuals and individuals with schizophrenia. This study is not intended to diagnose, cure or treat schizophrenia or any other disease.
Eligibility Criteria
Inclusion Criteria: * between ages of 18 and 50 * ability to sufficiently speak and understand English so as to be able to understand and complete cognitive tasks * ability to give valid informed consent Exclusion Criteria: * no history of head trauma * no current or previous history of treatment with psychotropic medication * corrected vision 20/30 or better * tDCS/MRI contraindications, including: pregnancy, ferrous metal in any part of the body, serious medical conditions, claustrophobia, metallic implants, skin damage, conditions such as eczema at electrode sites, cranial pathologies
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04885322 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04885322 currently recruiting?
Yes, NCT04885322 is actively recruiting participants. Contact the research team at mihchu@ucdavis.edu for enrollment information.
Where is the NCT04885322 trial being conducted?
This trial is being conducted at Sacramento, United States.
Who is sponsoring the NCT04885322 clinical trial?
NCT04885322 is sponsored by University of California, Davis. The trial plans to enroll 75 participants.