NCT06989138 Effects of Orthosis & Exercise on Spondylolisthesis
| NCT ID | NCT06989138 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medipol University |
| Condition | Spondylolisthesis |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2025-07-26 |
| Primary Completion | 2026-11 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2025-07-26 with a primary completion date of 2026-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In the treatment of spondylolisthesis, conservative methods are initially preferred unless severe neurological symptoms are present; surgical treatment is only performed in refractory cases lasting at least 3-6 months. Conservative treatment consists of orthotic use, activity restriction, pain control, physiotherapy and exercise. Orthotics may promote healing by restricting movement; however, there are not enough studies on this subject. Exercise is the intervention with the highest level of evidence in chronic low back pain. The efficacy of stabilisation exercises in providing positive and long-lasting effects on pain and functional disability in patients with spondylolisthesis has been demonstrated. However, studies evaluating the effect of exercise on spinal stability and radiological findings are limited. Therefore, this study aims to compare the effects of stabilization and conventional exercises with orthosis on radiographic findings, pain, physical function and quality of life.
Eligibility Criteria
Inclusion Criteria: * Individuals aged 18-65 * Individuals without indication for surgery * Individuals diagnosed with grade 1-2 spondylolysis * Individuals without neurological deficits * Individuals diagnosed with radicular pain or non-specific chronic low back pain for more than 3 months Exclusion Criteria: * Surgery recommended after diagnosis * History of lumbar surgery * Presence of rheumatic inflammatory diseases or diabetic polyneuropathy * Individuals with symptoms of cauda equina or ischemic heart disease * Presence of back pain with non-mechanical causes or non-radicular neuropathic pain * Having received this type of exercise therapy before
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06989138 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Spondylolisthesis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06989138 currently recruiting?
Yes, NCT06989138 is actively recruiting participants. Contact the research team at dilge.asik@medipol.edu.tr for enrollment information.
Where is the NCT06989138 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT06989138 clinical trial?
NCT06989138 is sponsored by Medipol University. The trial plans to enroll 48 participants.